Post Prostatectomy : 10yr PFS : No Adjuvant/Salvage Therapy

Stephenson AJ1, Scardino PT, Eastham JA, Bianco FJ Jr, Dotan ZA, DiBlasio CJ, Reuther A, Klein EA, Kattan MW.
Postoperative nomogram predicting the 10-year probability of prostate cancer recurrence after radical prostatectomy.
J Clin Oncol. 2005 Oct 1;23(28):7005-12.

The 10-year progression-free probability for the modeling set was 79% (95% CI, 75% to 82%). Significant variables in the multivariable model included PSA (P = .002), primary (P < .0001) and secondary Gleason grade (P = .0006), extracapsular extension (P < .0001), positive surgical margins (P = .028), seminal vesicle invasion (P < .0001), lymph node involvement (P = .030), treatment year (P = .008), and adjuvant radiotherapy (P = .046). The concordance index of the nomogram when applied to the independent validation sets was 0.81 and 0.79.

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