Hello all,

I am wondering if you could help me with the concept of multi-fraction survival curve.

I want to plot the survival curve as a function of dose for a number of dose fractions.

For example, I have a 60 Gy delivered over 4 fractions. Is it right to use the following equation:

S = e^{(n*(-alpha * Dose - beta *Dose^2))} .

n is number of fractions and Dose = 60/4= 15 Gy per fraction.

However, this gives me only one point! and I need to plot four different curves at a specific dose fractions (duplicate the shoulder of the curve n times). I tried to post the plot that I want but I am not allowed to do so.

Any help will be appreciated!

Thank you